TOR inhibitors following heart transplant

Authors: L. Špinarová
Published in: Kardiol Rev Int Med 2011, 13(1): 44-47
Category: From Heart Failure to Heart Transplantation


This is an overview of the use of new immuno­suppressive medication – TOR inhibitors – including everolimus and sirolimus on patients following heart transplants. It is possible to administer these medicaments de novo or to switch from existing therapy. Indicators for a switch are calcineurin nephropathy, vasculopathies, malignities, myopathies and neurotoxicity. These medicaments thus increase the options for immunosuppression, with treatment administered according to any accompanying illnesses suffered by patients.

transplants – TOR inhibitors – immunosuppression


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Paediatric cardiology Internal medicine Cardiac surgery Cardiology
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